E25: Jeff Galvin, CEO of Addimmune on Finding a Cure for HIV
The 10X Capital Podcast
The 10X Capital Podcast is a podcast that interviews the world's leading institutional investors. Previous guests include The Ford Foundation, Northwestern University Endowment, CalPERS, Stepstone, and other top limited partners.
David Weisburd
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PodcastAI

E25: Jeff Galvin, CEO of Addimmune on Finding a Cure for HIV

E25 • Dec 6, 2023 • 34 mins

Jeff Galvin, CEO of Addimmune, sits down with David Weisburd to discuss cell and gene therapy, and how Addimmune is working on a functional solution for HIV. We’re proudly sponsored by Bidav Insurance Group, visit lux-str.com if you’re ready to level up your insurance plans.

Key Points

  • In phase 1 trials, AGT 103-T showed no serious adverse events and indicated potential efficacy through blood markers, demonstrating safety and a positive response in HIV patients who remained on antiretrovirals.
  • The anti-retroviral withdrawal study with AGT 103-T revealed that treated patients maintained stable CD4 counts and had an increase in CD8 cells, suggesting an effective immune response against HIV when antiretrovirals were stopped.
  • American Gene Technologies (AGT) is working towards a public listing with the support of 10x Capital and is part of a broader gene and cell therapy revolution that aims to transition from treating to curing diseases, with around 30 approved therapies already in the market.
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